Alfie Deyes started his PointlessBlog YouTube channel in 2009. As of July 2014, Deyes has over 2.6 million subscribers and over 116 million views on YouTube. He also has a following of over 1 million followers on Twitter and over 1 million followers on Instagram. He was named by Yahoo! News as one of "12 Web-savvy entrepreneurs to watch" in December 2013, and was featured on the cover of the January 2014 edition of Company magazine for the "Generation Youtube" feature.

Deyes has collaborated with a number of other Youtubers; including Tanya Burr, Louis Cole, Louise Pentland, Grace Helbig, Harley Morenstein (EpicMealTime), Tyler Oakley, Troye Sivan and Zoe Sugg. He also created a couple of videos with Ariana Grande for the You Generation network on YouTube.

He currently stars, along with a number of other youtubers, in the Style Haul series "The Crew," described by teen website Sugarscape.com as "the male version of Loose Women, but a bit less pervy."

In 2013, Deyes was a member of the "Guinness World Records OMG!" channel and held a number of world records, including "Most bangles put on in 30 seconds by a team of two," along with Youtubers Marcus Butler and 'Laurbubble' (which they still hold); and "Most party poppers popped in 30 seconds" with a count of 29, beating the previously set record by 1 (he subsequently lost this to Ashrita Furman in October 2013).

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