Donna started her career age 10 on the hit CBBC series Byker Grove. She then became part of pop duo Crush touring the United States, Japan and South East Asia, returned to the United Kingdom after signing to MTV hosting daily live show - MTV Select, and later became a presenter of several shows, including, The Big Breakfast for Channel 4, TFI Friday with Huey Morgan (from Fun Lovin' Criminals), Popstars: The Rivals Extra for ITV (the show that created Girls Aloud), to name a few. She has also acted in many television dramas, most recently Hollyoaks and Hotel Babylon, BBC TV comedy Operation Good Guys, Catherine Cookson's six-parter A Dinner of Herbs, and Lynda La Plante's Supply and Demand. Air appeared in the films Still Crazy, The Mummy Returns, and Bad Day amongst others.

Air presented on Five's early evening, magazine programme Live from Studio Five, alongside regular presenter of the programme, Kate Walsh. Air is also is a brand ambassador for Health Lottery, Burberry, Next, Westfield, Olay, Cadbury's and Triumph.

Donna has worked with the Soil Association, promoting organic milk, launching the Nursery Food report at Downing Street, and edited the Grown in Britain cookbook.

In January 2013, Air came 4th in the ITV programme, Splash! She replaced Jennifer Metcalfe, shortly after Jennifer's split from Dancing On Ice pro Sylvain Longchambon.

In 2019, Air was announced as having a starring role in the second series of the drama The Split, which started airing on BBC One in February 2020.

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