Jason began acting at the age of five. In 1991, he made his television debut in the Fox network series "Drexell's Class." That same year, Biggs debuted on Broadway in "Conversations With My Father," which helped pave the way for Biggs to participate in the daytime soap opera, "As the World Turns." He was nominated for the award of Best Younger Actor at the daytime Emmy awards for his role in that soap.

Jason Biggs attended New York University from 1996 to 1997 and appeared in the television series "Camp Stories."

In 1999 Biggs starred as Jim Levenstein in "American Pie," which went on to become an international hit that spawned three sequels. After that, Biggs accepted starring roles in movies such as 2000's "Loser" and others.

He appeared in the 2002 Broadway production of "The Graduate" as Benjamin Braddock alongside Kathleen Turner and Alicia Silverstone. In 2003, Biggs appeared as Jerry Falk in the Woody Allen romantic comedy "Anything Else." In the 2004–2005 season Biggs portrayed an Orthodox Jew in Daniel Goldfarb's comedy, "Modern Orthodox," staged at Dodger Stages theater in New York City.

In 2006, Biggs was seen in the MTV reality show "Blowin' Up with Jamie Kennedy and Stu Stone," which led to his participation in a hip-hop recording with Bay Area rapper E-40.

Biggs returned to the stage in the fall of 2008 in Howard Korder's "Boys' Life" at New York City's Second Stage Theatre.

Biggs has appeared in several other films, including "Texas Rangers," "Scary Movie" and "Over Her Dead Body."

In 2010, Biggs made his literary debut by contributing "Scratch-and-Sniff," a poem about growing up in New Jersey, to the anthology "What's Your Exit? A Literary Detour through New Jersey," alongside writers such as Joyce Carol Oates, Tom Perrotta, Robert Pinsky, Gerald Stern and J. Robert Lennon.

In the summer of 2012, Biggs took a job voicing Leonardo on Nickelodeon in "Teenage Mutant Ninja Turtles."

Biggs currently stars in the acclaimed series "Orange Is The New Black."

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