Lily Gladstone is an actress of Blackfeet and Nimíipuu heritage. Her film career began with her debut in Jimmy P: Psychotherapy of a Plains Indian in 2012, and she soon established a productive collaboration with filmmaker Kelly Reichardt, participating in Certain Women in 2016 and First Cow in 2019. Gladstone's portrayal of a rancher in Certain Women earned her not only a nomination for the Independent Spirit Award for Best Supporting Female but also the Los Angeles Film Critics Association Award for Best Supporting Actress in 2016.

Expanding her acting reach, Gladstone made appearances in television series, including HBO's "Room 104", Showtime's "Billions," and FX's "Reservation Dogs." In 2023, her performance in Martin Scorsese's drama film Killers of the Flower Moon received widespread critical acclaim, earning her a Golden Globe Award for Best Actress in a Motion Picture - Drama, making her the first Native American to receive this award. This performance also garnered Gladstone a nomination for the Academy Award for Best Actress and won her several other awards including the Boston Society of Film Critics Award, Florida Film Critics Circle Award, National Board of Review Award, New York Film Critics Circle Award, San Diego Film Critics Society Award, St. Louis Gateway Film Critics Association Award, Toronto Film Critics Association Award for Outstanding Lead Performance, Dallas-Fort Worth Film Critics Association Award, and Washington D.C. Area Film Critics Association Award all for Best Actress in 2023.

In addition to her acting career, Gladstone is also an educator. She graduated from the University of Montana with a Bachelor of Fine Arts in Acting/Directing and has hosted a series on film production for the educational YouTube channel Crash Course.

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