Mary-Louise Parker is a stage and screen leading lady who is best known for her role as a suburban dope dealer in the cable TV series Weeds. On Broadway she won rave reviews for Prelude to a Kiss (1990-91) and a Tony Award for Proof (2000-03). She made her mark on the big screen in Fried Green Tomatoes (1991) and Boys on the Side (1995), and and even bigger impression on TV, with the miniseries Angels in America (2003), for which she received a Golden Globe and an Emmy Award for Best Supporting Actress, and a recurring role as Amy Gardner on The West Wing (2001-06). Since 2005 she's been the star of the successful series Weeds, while still appearing on stage and in films, including The Assassination of Jesse James by the Coward Robert Ford (2007, opposite Brad Pitt) and The Spiderwick Chronicles (2008).

Parker starred opposite Bruce Willis in the film RED, an adaptation of the comic book mini-series of the same name. The film was released on October 15, 2010. In 2011, Parker became the host for the tenth season of the PBS documentary series Independent Lens. In 2013 she played roles in both RED 2 and R.I.P.D. She appeared in the Broadway Manhattan Theatre Club production of the play The Snow Geese by Sharr White at the Samuel J. Friedman Theatre from October 24 through December 15, 2013. The play was directed by Daniel J. Sullivan and also starred Danny Burstein and Victoria Clark.

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