Since her start on Saturday Night Live in 1999, Dratch's versatility has helped her build quite a list of memorable characters. Her tenure at SNL spanned 1999 to 2006. Dratch's recurring characters included Boston teen Denise; Sheldon, the junior-high-school boy from Wake up, Wakefield; the Lovers (with Will Ferrell, as two pretentious professors); Abe Scheinwald, a Hollywood producer; and Debbie Downer, a depressed woman who creeped others out with disturbing non sequiturs.

In 2000, she and Tina Fey put on their two-woman show, "Dratch & Fey," at the Upright Citizens Brigade Theater in New York. And in 2001, Dratch wrote, directed and performed in a short film called "The Vagina Monologues Monologues," which also featured Fey and SNL performer Amy Poehler. It premiered at the New York Comedy Film Festival.

She has appeared in the movie "Down With Love" and the independent film "The Hebrew Hammer." Dratch's other movie credits include "Martin & Orloff," "Dickie Roberts: Former Child Star," "Click," "I Now Pronounce You Chuck and Larry," "Spring Breakdown" and "My Life in Ruins."

Her television appearances include "Late Night with Conan O'Brien," CBS' "King of Queens" and "Third Watch." Dratch and Fey left SNL after the 2005-2006 season to try their luck on a primetime slot with "30 Rock," a sitcom about a television writer (played by Fey) and her supporting cast.

Dratch attended the National Theater Institute in the fall of 1986, and graduated from Dartmouth College in 1988, where she majored in drama and psychology and was a member of the improvisational comedy group "Said and Done."

In 2012, Dratch's memoir, Girl Walks into a Bar: Comedy Calamities, Dating Disasters, and a Midlife Miracle was published. In it, Dratch recounts her experiences after being recast in the 30 Rock pilot, including the birth of her first child.

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