Middleton gained a following for her appearance in the 2009 British horror/comedy "Tormented." Her character, head girl Justine Fielding, dates one of the most popular boys in school, only to find that he and his friends were responsible for a classmate's death. She has also appeared in adverts for the chewing gum Extra and Sky TV.

In 2010 she starred in Samuel Abrahams's BAFTA-nominated short film "Connect." In 2011, she played the character Tanya Greene in the British sitcom "Friday Night Dinner," and "Sarah in Sirens." In 2012 she appeared in "Cleanskin," a terrorist thriller. In March 2013 she made her professional theatre debut in "The Living Room." She also played a minor role in the Danny Boyle film "Trance." In 2015, she starred in the Netflix Original Series "Sense8", as Riley Blue.

Entertainers, Television Actress, Actress, Broadway, Movie Actress, British / English, Celebrity, Entertainment Industry, Women in Entertainment, Netflix, Actors, Acting, Entertainment