Vince Papale is a former professional American football player. He played three seasons with the Philadelphia Eagles of the NFL following two seasons with the Philadelphia Bell of the World Football League. Papale was the inspiration for the 2006 movie Invincible.

Vince Papale's post-collegiate football career began with the Aston Green Knights of the semi-pro Seaboard Football League. At that time, Papale was a teacher at Interboro High School and was coaching the junior varsity football team when he successfully tried out for the Philadelphia Bell of the World Football League as a wide receiver. In his first season with the Bell, Papale caught nine passes for 121 yards, averaging 13.4 yards per catch. In 1975 Papale caught only one pass, but it was for a forty-nine yard touchdown. In both seasons with the team, Papale was a special teams standout.

His performance with that team earned him a meeting in 1976 with head coach Dick Vermeil of the Philadelphia Eagles after general manager Jim Murray got him an invitation to a private workout held by Coach Vermeil.

Papale eventually made the team, thereby becoming, at age 30, the oldest rookie in the history of the NFL to play without the benefit of college football experience (other than kickers). He went on to play wide receiver and special teams for the Eagles from 1976 through 1978. During that time, he played in 41 of 44 regular season games (regular seasons being 14 games in 1976–1977 and 16 games in 1978) recording two fumble recoveries and one 15-yard reception. He was voted Special Teams Captain by his teammates and "Man of the Year" by the Eagles in 1978 for his many charitable activities. A shoulder injury ended his career in 1979. After retiring from the NFL, he worked as a TV and radio broadcaster for eight years, then became a commercial mortgage banker.

Diagnosed with colorectal cancer in 2001, Papale has recovered from the disease, to become a spokesman encouraging people to get regular check-ups. "I am a big-time advocate of colorectal screening for people my age, especially men who might think it's not macho, because it saved my life," said Papale. "My mission is to save lives. A single screening examination performed on people with no symptoms beginning at age 40 - 50 will greatly increase the chances of long-term survival from the disease or preventing it altogether."

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