Bierko got his big break in 1990 when he was cast opposite Valerie Bertinelli and Matthew Perry in the CBS sitcom Sydney; however, the production lasted just 13 episodes.

He went on to make steady appearances in various television shows including Amen, The Powers That Be, Wings and Ally McBeal.

He also played Tom Ryan in Scary Movie 4 (spoofing Tom Cruise throughout the film) and on the Broadway stage as Harold Hill in The Music Man.

He was also the original choice for the character of Chandler Bing on the sitcom Friends but turned it down. He had a short role as Carrie Bradshaw (Sarah Jessica Parker)'s jazz musician love interest in the fourth season of Sex and the City.

He had another short role as attorney Jeffrey Coho during the third season of the ABC television series Boston Legal and as a lead in the short-lived Unhitched.

He was also cast as Dave Lister in the pilot for the American version of Red Dwarf, which was not picked up as a series. He appeared in 2001's Kate and Leopold in an uncredited role.

Bierko was slated to appear on Broadway in the Manhattan Theatre Club production of To Be or Not to Be but withdrew from the production August 29, 2008, for unspecified reasons.

He starred as Sky Masterson in the Broadway revival of Guys and Dolls which began performances at the Nederlander Theatre on February 5, 2009, and officially opened on March 1, 2009.

The production closed on June 14, 2009 after 113 performances

Entertainers, Comedians, Non-Profit & Association, Philanthropy, Theatre, Artists, Literary, Celebrity Charity, Comedy,